METHOD FOR PRODUCING (2S,5R)-7-OXO-6-SULPHOXI-2-[((3R)-PIPERIDINE-3-CARBONYL)HYDRAZINOCARBONYL]-1,6-DIAZABICYCLO[3,2,1]OCTANE Russian patent published in 2017 - IPC C07D471/08 

Abstract RU 2627700 C2

FIELD: chemistry.

SUBSTANCE: invention relates to method for obtaining compound of Formula

,

comprising: (a) reaction between compound of Formula

and compound of Formula

in the presence of water taken as solvent to obtain compound of Formula

;

(b) hydrogenolysis of compound of Formula (IV) to obtain compound of Formula

;

(c) sulfonation of compound of Formula (V) to obtain compound of Formula

;

and (d) conversion of compound of Formula (VI) to compound of Formula (I). The invention also relates to method of producing compound of formula (I).

EFFECT: simplicity of operations, safer conditions, high yield of the target product.

10 cl, 1 dwg, 2 ex

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RU 2 627 700 C2

Authors

Dzhoshi Sandzhiv

Vankkhede Karuna Suresh

Dzhadkhav Sunil Bkhaginat

Pavar Shivadzhi Sampatrao

Akhirrao Vinod Kashinat

Bkhavsar Satish

Deshpande Prasad Keshav

Jeole Ravindra Dattatraya

Patel Makhesh Vitkhalbkhaj

Dates

2017-08-10Published

2013-10-12Filed