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2 627 897

(13)

(51)

IPC

A61K39/10(2006-01-01)

A61P31/00(2006-01-01)

(21) (22)

Application

2016140512, 2016-10-14

(24)

Start date

2016-10-14

(22)

Actual filing date

2016-10-14

(45)

Published

2017-08-14

(72)

Inventor

Fedorov Andrej IvanovichIskandarov Marat IdrisovichAlbertyan Mkrtich PogosovichIskandarova Salmikhanum SamurkhanovnaGulyukin Mikhail Ivanovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Nauchnoe Uchrezhdenie Vserossijskij Nauchno-Issledovatelskij Institut Eksperimentalnoj Veterinarii Imeni Ya.R. Kovalenko

METHOD FOR OBTAINING OF ANTIGEN FOR DETERMINATION OF ANTIBRUCELLAR IMMUNITY Russian patent published in 2017 - IPC A61K39/10 A61P31/00

Abstract RU 2627897 C1

FIELD: medicine.

SUBSTANCE: method comprises culturing a brucella culture in a liquid nutrient medium, followed by desired product isolation. Cultivation is carried out at a temperature of 39-40 for 18-24 hours, followed by an increase in temperature to 45-50 within 6-10 hours and an increase in temperature to 60 degrees for 1-2 hours, followed by separation of the bacmass and antigen isolation from the culture medium.

EFFECT: use of this method allows to obtain the brucella antigen, by means of which it is possible to carry out objective monitoring of immunity level induced in animals in response to the introduction of antibrucellar vaccines.

2 cl, 4 tbl, 36 ex

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RU 2 627 897 C1

Authors

Fedorov Andrej Ivanovich

Iskandarov Marat Idrisovich

Albertyan Mkrtich Pogosovich

Iskandarova Salmikhanum Samurkhanovna

Gulyukin Mikhail Ivanovich

Dates

2017-08-14—Published

2016-10-14—Filed