PIPERAZINO[1,2-A]INDOLE-1-ONES AND [1,4] DIAZEPTINO[1,2-A]INDOLE-1-ONE Russian patent published in 2017 - IPC C07D487/04 A61K31/4985 A61K31/551 A61P25/00 

Abstract RU 2628126 C2

FIELD: medicine.

SUBSTANCE: invention relates to application of compounds of general formula I .

EFFECT: new compounds, as well as pharmaceutical compositions based thereon, are obtained, that can be used to treat schizophrenia, obsessive-compulsive personality disorder, major depression, bipolar disorder, anxiety disorders, normal aging, epilepsy, retinal degeneration, traumatic brain injury, spinal cord injury, post traumatic stress disorder, panic disorder, Parkinson's disease, dementia, Alzheimer's disease, mild cognitive impairment, chemotherapy-induced cognitive dysfunction, Down's syndrome, autism spectrum disorders, hearing loss, tinnitus, spinocerebellar ataxia, amyotrophic lateral sclerosis, multiple sclerosis, Huntington's disease, stroke, and violations resulting from radiation therapy, chronic stress or abuse of neuroactive drugs, such as alcohol, opiates, methamphetamine, phencyclidine or cocaine.

11 cl, 1 tbl, 46 ex

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RU 2 628 126 C2

Authors

Dzhagasia Ravi

Yakob-Roetne Roland

Vikhmann Yurgen

Dates

2017-08-15Published

2014-03-31Filed