BICYCLIC PIPERAZINE COMPOUNDS Russian patent published in 2017 - IPC C07D471/04 C07D495/04 A61K31/437 A61K31/4985 A61P35/00 A61P37/00 

Abstract RU 2628616 C2

FIELD: pharmacology.

SUBSTANCE: invention relates to new bicyclic piperazine compounds of formula

,

as well as to pharmaceutically acceptable salts thereof.

EFFECT: new compounds of formula I have been obtained that have modulating activity against Bruton tyrosine kinase, that can be used to prepare pharmaceutical compositions, as well as for treatment of immune disorders such as inflammation mediated by kinase.

17 cl, 15 dwg, 2 tbl, 131 ex

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RU 2 628 616 C2

Authors

Krouford Dzhejms Dzhon

Ortvajn Daniel Fred

Yang Vendi B.

Dates

2017-08-21Published

2012-11-02Filed