FIELD: pharmacology.
SUBSTANCE: invention relates to new bicyclic piperazine compounds of formula
,
as well as to pharmaceutically acceptable salts thereof.
EFFECT: new compounds of formula I have been obtained that have modulating activity against Bruton tyrosine kinase, that can be used to prepare pharmaceutical compositions, as well as for treatment of immune disorders such as inflammation mediated by kinase.
17 cl, 15 dwg, 2 tbl, 131 ex
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