FIELD: pharmacology.
SUBSTANCE: proteolytic enzyme substance based on Protosubtilin GZH and a composition for purulent-necrotic wounds treatment are proposed. The proteolytic enzyme substance immobilized on chitosan activated by glutaraldehyde has an enzymatic activity of 17-19 units of neutral protease activity/g of wet weight. The composition for treatment of purulent-necrotic wounds contains the proteolytic enzyme substance based on Protosubtilin GZH as the main component, T-2 emulsifier, Tween 20 and 0.05% chlorhexidine bigluconate solution as the target additives, vaseline oil as a base.
EFFECT: increased purity of the proteolytic enzyme and increased wound healing properties of the composition.
2 cl, 1 dwg, 4 tbl, 10 ex
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|---|---|---|---|
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|
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