PHARMACEUTICAL SUBSTANCE FOR TREATING INFECTED WOUNDS OF VARIOUS ORIGINS Russian patent published in 2019 - IPC A61K47/18 A61K47/38 A61K31/131 A61K31/722 A61P31/00 

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention refers to pharmaceutics, namely to a pharmaceutical substance for preparing a medicinal agent for treating infected wounds. Substance is characterized by the inclusion of an effective amount of the active ingredients miramistin and chitosan, as well as acetic acid as an adjuvant and water with the following ingredients content, wt. %: Miramistin - 0.05, Chitosan - 1.0, Acetic acid - 0.6, Purified water - up to 100.0. Method of producing a pharmaceutical substance is characterized by the fact that chitosan is mixed with 0.5 % acetic acid solution, continuously mixed and poured water to obtain a suspension, mixed until complete dissolution of chitosan and left to stand until a gel-like solution is obtained, then the antimicrobial preparation Miramistin is immobilized on chitosan at room temperature at a weight ratio of chitosan to miramistin 20:1 and is obtained by lyophilisation at -40 °C chitosan and miramistin substance in the form of a spongy cancellous mass, wherein water is removed from frozen substance by sublimation of ice.

EFFECT: invention enables to obtain a biologically active compound: a chitosan complex with an antimicrobial preparation miramistin (CCM), as well as a wider range of wound healing and antimicrobial agents.

1 cl, 7 dwg, 3 ex