FIELD: pharmacology.
SUBSTANCE: drug can be used in therapy, in particular in cardiology, and in sports medicine. Preferably, the pharmaceutical composition for oral use in the form of a pill contains hemihydrate, magnesium aspartate dihydrate, microcrystalline cellulose, sodium croscarmellose, aerosil, stearic acid in the potassium asparaginate; the pill shell contains the pH-dependent polymer Eudragit, polyethylene glycol, talc, titanium dioxide. A method for manufacture of a tablet with asparaginates is also described. The composition is characterized by delayed, after 2 hours, release of active ingredients and subsequent rapid release of these active substances in a therapeutically active concentration within 20-30 minutes.
EFFECT: reduced side effects on the gastric mucosa.
16 cl, 11 dwg, 1 tbl, 11 ex
