STABILIZED CARDIOLYPINE ANTIGEN FOR THE REACTION OF MICROPRECIPITATION WITH SYPHILISIS DIAGNOSIS AND THE METHOD OF ITS RECEPTION Russian patent published in 2017 - IPC G01N33/53 

Abstract RU 2633087 C2

FIELD: medicine.

SUBSTANCE: declared stable cardiolipin antigen and preparation method thereof. Cardiolipin antigen obtained by a process comprising preparing a buffer solution with the sequential addition of one another EDTA disodium salt, sodium phosphate 2-substituted potassium phosphate 1-substituted, choline chloride, thimerosal (thimerosal), purified water, then the resulting solution was stirred and filtered, after which the prepared alcoholic lipid solution was mixed to this cardiolipin, lecithin, and cholesterol, absolute ethyl alcohol, then mixing performed buffer solution and spirit solution.

EFFECT: complete cycle producing ready-to-use suspension cardiolipin antigen on the production plant, quality control and ensuring long prepared reagent specific activity in the reaction microprecipitation in the diagnosis of syphilis with the exception of laboratory stage of preparation of the working emulsion Ag Cl.

2 cl, 2 ex

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Authors

Mardanly Sejfaddin Gashim Ogly

Amelina Elena Anatolevna

Bakhilina Natalya Vladimirovna

Ermolaeva Irina Anatolevna

Rotanov Sergej Vladimirovich

Dates

2017-10-11Published

2016-03-23Filed