SULFO-CONTAINING POLYMERS WITH ITS OWN ANTIVIRAL ACTIVITY Russian patent published in 2017 - IPC C08F120/56 C08F220/56 A61P31/12 A61K31/785 A61K31/795 

Abstract RU 2635558 C2

FIELD: pharmacology.

SUBSTANCE: invention relates to the high-molecular weight compounds of the medical purpose, more specifically to new synthetical sulfo-containing homo- and copolymers 2-acrylamido-2-methylpropansulfoacid with its own bioactivity that can be used in pharmacology in the capacity of the future-proof antiviral agents or can serve as the basis for the new effective and harmless antiviral medicinal agents and its pharmaceutical forms. The homo- and copolymers 2-acrylamido-2-methylpropansulfoacid of the stated below formula are obtained by the radical heterophase (co)polymerization in the ethanol at 70°C within 24 hours. The homo- and copolymers 2-acrylamido-2-methylpropansulfoacid have the molecular weight MM=(40-70)⋅103.

where

,

m=100 mol. %, n=0;

,

m=(22.8-58.1) mol. %, n=(77.2-41.9) mol. %.

EFFECT: invention allows to get nontoxical homo- and copolymer 2-acrylamido-2-methylpropansulfoacid with its own antiviral activity against the influenza viruses H3N2, H1N1.

1 tbl, 2 ex

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RU 2 635 558 C2

Authors

Smirnova Marianna Yurevna

Solovskij Mikhail Vasilevich

Eropkina Elena Mikhajlovna

Eropkin Mikhail Yurevich

Dates

2017-11-14Published

2016-04-06Filed