PEPTIDE-BASED COMPOSITION SUPPRESSING REPLICATION OF INFLUENZA A VIRUS Russian patent published in 2019 - IPC A61K38/04 A61K38/08 A61K8/64 A61K31/95 A61K31/45 A61P31/16 

Abstract RU 2695336 C1

FIELD: medicine; pharmaceuticals.

SUBSTANCE: present invention refers to pharmaceutical industry, namely to an oligopeptide-based composition which suppresses replication of influenza A virus. A composition for treating influenza on the basis of oligopeptide, suppressing replication of influenza A virus, sequence 6–14 of protein of polymer complex PB1 of influenza virus, acetylated by N-terminal and amidated by C-terminal, formula Ac-Thr-Leu-Leu-Phe-Leu-Lys-Val-Pro-Ala-NH2, which additionally contains dimethylsulphoxide, ethanol and water, taken in certain amounts.

EFFECT: disclosed oligopeptide-based composition is stable and has high solubility of the oligopeptide.

1 cl, 6 tbl

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RU 2 695 336 C1

Authors

Egorov Vladimir Valerevich

Zabrodskaya Yana Aleksandrovna

Shaldzhyan Aram Arutyunovich

Matusevich Oleg Vladimirovich

Vasin Andrej Vladimirovich

Shtro Anna Andreevna

Sergeeva Mariya Valerevna

Nikonov Boris Alekseevich

Garshinina Anzhelika Valerevna

Fedorova Viktoriya Aleksandrovna

Gorshkov Andrej Nikolaevich

Zarubaev Vladimir Viktorovich

Gyulikhandanova Nataliya Evgenevna

Dates

2019-07-23Published

2018-06-27Filed