FIELD: chemistry.
SUBSTANCE: present invention relates to sulphonated copolymers having antiviral activity on human respiratory syncytial virus A-2. Copolymers are compounds of formula: [A]m[B]n, in which A is a sodium styrene sulphonate unit, B is a vinyl comonomer unit, m=1÷93 mol.%, n=100 mol.%. Intrinsic viscosity of copolymers [η] is 0.22–1.34 dl/g in 0.1 n NaCl at 25 °C. Copolymers are obtained by radical copolymerisation in water or an aqueous-organic solvent in the presence of a radical initiator.
EFFECT: obtained copolymers have low cytotoxicity and high antiviral activity with respect to human respiratory syncytial virus A-2.
1 cl, 1 tbl, 11 ex
| Title | Year | Author | Number |
|---|---|---|---|
| WATER-SOLUBLE COPOLYMERS OF HYDROXYCINNAMIC ACID WITH VINYL COMONOMERS, ACTIVE AGAINST INFLUENZA AND HERPES VIRUSES | 2024 |
|
RU2841381C1 |
| COPOLYMERS OF N-VINYLAMIDES WITH SALTS OF HYDROXYCINNAMIC ACID | 2022 |
|
RU2796753C1 |
| 2-(1,2,3-TRIAZOLYL)SUBSTITUTED LINEAR FUROCOUMARINS HAVING ANTIVIRAL ACTIVITY AGAINST INFLUENZA A/H1N1 VIRUS | 2024 |
|
RU2841063C1 |
| METHOD OF PREVENTING RESPIRATORY VIRAL INFECTIONS (FLU) | 2022 |
|
RU2805806C1 |
| METHOD OF PRODUCING WATER-SOLUBLE COPOLYMERS OF N-VINYL AMIDES CONTAINING ALDEHYDE GROUPS | 2015 |
|
RU2594253C1 |
| SULFO-CONTAINING POLYMERS WITH ITS OWN ANTIVIRAL ACTIVITY | 2016 |
|
RU2635558C2 |
| METHOD OF PRODUCING SYNTHETIC METAL-POLYMER COMPLEXES OF RADIOISOTOPE GALLIUM-68 | 2015 |
|
RU2588144C1 |
| METHOD OF PRODUCING CARBOHYDRATE-CONTAINING POLYMERS | 2012 |
|
RU2538211C2 |
| WATER-SOLUBLE COPOLYMERS OF VINYLPHOSPHONIC ACID | 2022 |
|
RU2788168C1 |
| 3-SUBSTITUTED 6-(METHOXYCARBONYL)UMBELLIFERONES, HAVING INHIBITORY ACTIVITY ON INFLUENZA VIRUS A/H1N1 | 2024 |
|
RU2838462C1 |
