FIELD: biotechnology.
SUBSTANCE: variants of antibodies binding tumour-associated antigenic polypeptide TAT425 are proposed. Nucleic acids encoding the antibodies of the invention; a method for determining the presence of TAT425 protein in a sample and a method for diagnosing the presence of a tumour are also contemplated. The invention can find its further application in diagnosing and treating cancer.
EFFECT: improved properties of the composition.
26 cl, 10 dwg, 1 tbl, 16 ex
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