METHOD FOR PREDICTING RISK OF DEVELOPING MULTIOCULAR SCLEROSIS IN PATIENTS WITH SUBACUTE COURSE OF OPTIC NEURITIS Russian patent published in 2017 - IPC G01N33/493 G01N33/50 G01N33/53 

FIELD: medicine.

SUBSTANCE: invention is designed to predict the development of multiocular sclerosis (MS) in patients with subacute course of optic neuritis (ON). In serum, the level of optical density for antibodies of IgM class to the antigen of the retina is determined. Magnitude of peak latency and amplitude of the R100 visual evoked potentials (VEP), amplitude of N95 pattern-electroretinogram (PERG), photopic negative response to the conicus ERG (FNR). When the level of optical density for IgM class antibodies to retina S-antigen is equal and more than 0.15, extending of peak latency of R100 VEP at 20% or more, reducing the amplitude of N95 ERG and/or amplitude of FNR to 20% or more the development of multiocular sclerosis is predicted.

EFFECT: use of the invention makes it possible to provide specialized assistance in a timely manner in order to prevent the aggravation of the course of multiple sclerosis.

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