FIELD: pharmacology.
SUBSTANCE: invention relates to the phthalazine derivatives that are represented by the formula I 
,
where the radicals and symbols have the definitions indicated in the formula of the invention. The compounds of the formula I are activity inhibitors of the poly(ADP-ribose) polymerase ferment. The invention also relates to the pharmaceutical composition for cancer treatment, which comprises the compound of the formula I, to the method of cancer treatment and to the compound application for the medicinal agent for cancer treatment production.
EFFECT: compound application efficiency upgrading.
16 cl, 8 tbl, 176 ex
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