MEANS FOR INTESTINAL FIBROSIS TREATMENT Russian patent published in 2017 - IPC A61K47/54 C12N5/71 A61P43/00 

Abstract RU 2637372 C2

FIELD: pharmacology.

SUBSTANCE: invention refers to a carrier for a medicinal product for intestinal fibrosis treatment through medicinal product delivery to inhibit growth or activity of cells producing an extracellular matrix in the intestine, which can be used in medicine. The specified carrier contains retinoid and lipid where retinoid contributes to the drug delivery to these cells and intestinal fibrosis treatment, which is used in the pharmaceutical compositions for intestinal fibrosis treatment and regeneration of normal tissue of the intestine from the fibrous tissue, in a kit for reception of the specified pharmaceutical compositions, method for intestinal fibrosis treatment, as well as regeneration of normal tissue of the intestine from the fibrous tissue.

EFFECT: invention allows highly effective delivery of the extracellular matrix product inhibitor to the cell, producing the extracellular matrix, and inhibition of the expression of molecules involved in the extracellular matrix production.

15 cl, 4 dwg, 4 ex

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RU 2 637 372 C2

Authors

Ayabi Tokijoshi

Nakamura Kiminori

Minomi Kenzhiro

Tanaka Yasunobu

Dates

2017-12-04Published

2012-11-16Filed