FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to pharmaceutics. A method involves decreasing an amount or activity of CCL21 in fibrocytes and/or fibroblasts found in a fibrous defect site in said fibrous defect wherein decreasing the amount or activity of CCL21 provides the contact of said mammal with an agent decreasing the amount or activity of CCL21 in said fibroblasts. Said agent is introduced in the amount effective to relief one or more symptoms of said chronic fibrous defect.
EFFECT: group of inventions enables decreasing the number of fibrous defects and effectively treating symptoms of fibrous defects.
23 cl, 16 dwg, 5 ex
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