GEROPROTECTOR FOR MODEL ANIMALS Russian patent published in 2017 - IPC A61K31/7042 A61K31/7056 A61P39/00 

Abstract RU 2639500 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to application of 5-aminoimidazole-4-carboxamidiborofuranoside (AICAR) as a geroprotector in a nutrient medium for model animals. In case of nematodes, the geroprotective effect of AICAR is achieved in concentrations of 0.05 mM and 0.1 mM. In case of drosophila flies, the geroprotective effect of AICAR is achieved in concentrations of 0.5 mM and 1.0 mM.

EFFECT: increased life expectancy of model animals.

3 cl, 5 dwg, 3 ex

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RU 2 639 500 C1

Authors

Eremina Svetlana Yurevna

Shostak Nataliya Grigorevna

Zelentsova Elena Sergeevna

Katkova-Zhukotskaya Olga Aleksandrovna

Lobanov Konstantin Vladimirovich

Shakulov Rustem Saidovich

Funikov Sergej Yurevich

Mironov Aleksandr Sergeevich

Evgenev Mikhail Borisovich

Karpov Vadim Lvovich

Nudler Evgenij Aleksandrovich

Dates

2017-12-21Published

2016-09-02Filed