IMMUNITY INDUCING AGENT Russian patent published in 2017 - IPC A61K38/00 A61K39/00 A61P35/00 A61P37/04 

FIELD: medicine.

SUBSTANCE: invention refers to the immunity inducing agent containing the effective number of at least one polypeptide with inducing immune system activity, which induces cytotoxic t-cells capable to destroy tumour cells expressing polypeptide CAPRIN-1. Also, method is represented to obtain the selected antigen-presenting cell in vitro, which presents polypeptide fragment CAPRIN-1 for class I molecule RENAMO t-cells, as well as in vitro method for obtaining selected cytotoxic t-cells specific to protein CAPRIN-1. The invention also relates to a method of induction of immunity, including the introduction of individual effective amount of at least one polypeptide with inducing immune system activity, which induces cytotoxic t-cells capable to destroy tumour cells expressing polypeptide CAPRIN-1.

EFFECT: effectively destroys tumour cells expressing the CAPRIN-1 polypeptide.

13 cl, 5 dwg, 6 ex