FIELD: pharmacology.
SUBSTANCE: group of inventions refers to a local suspension composition that includes tetracycline, a liquid medium, and a polymeric gelling agent, and to a method for treatment of an infection or inflammation, including an ophthalmic disease, comprising administering ration of a topical suspension composition. The composition is characterized by tetracycline being in the form of its pharmaceutically acceptable salts, hydrates or polymorphs and is in suspended form in the composition, the liquid medium is selected so that it does not dissolve or substantially dissolve tetracycline, the gelling agent is a polymeric hydrocarbon gelling agent. Preferably, tetracycline has a particle size equal to or less than about 20 microns.
EFFECT: treatment of dermatological, ophthalmic and neurological diseases.
42 cl, 2 ex, 4 tbl
| Title |
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2016 |
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2019 |
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