RETINOID COMPOSITIONS FOR TOPICAL APPLICATION Russian patent published in 2019 - IPC A61K31/355 A61K31/4436 A61K31/7004 A61K8/49 A61P17/00 A61P19/00 A61Q19/02 A61Q19/08 A61Q19/10 

Abstract RU 2699027 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention refers to pharmaceutical industry and represents a topical composition for treating skin diseases, namely blackheads or psoriasis, or reducing wrinkles on skin, containing: a) a retinoid compound or a pharmaceutically acceptable salt thereof; b) at least one foaming additive; c) gluconolactone and tocofersolan as anti-irritants and d) one or more dermatologically acceptable excipients, wherein the gluconolactone content is not less than 0.25 % based on the total weight of the composition, the tocofersolan content is not less than 0.50 % based on the total weight of the composition, and the total content of said anti-irritants is less than 3 % based on total weight of composition.

EFFECT: invention provides suppressing irritation caused by retinoid compound, higher retinoid deposition, does not cause dry skin.

20 cl, 4 dwg, 11 tbl, 13 ex

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RU 2 699 027 C2

Authors

Kandavilli Sateesh

Bankar Manish M.

Dolai Sujit Kumar

Okumu Franklin

Dates

2019-09-03Published

2016-07-13Filed