FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention refers to pharmaceutical industry and represents a topical composition for treating skin diseases, namely blackheads or psoriasis, or reducing wrinkles on skin, containing: a) a retinoid compound or a pharmaceutically acceptable salt thereof; b) at least one foaming additive; c) gluconolactone and tocofersolan as anti-irritants and d) one or more dermatologically acceptable excipients, wherein the gluconolactone content is not less than 0.25 % based on the total weight of the composition, the tocofersolan content is not less than 0.50 % based on the total weight of the composition, and the total content of said anti-irritants is less than 3 % based on total weight of composition.
EFFECT: invention provides suppressing irritation caused by retinoid compound, higher retinoid deposition, does not cause dry skin.
20 cl, 4 dwg, 11 tbl, 13 ex
Title | Year | Author | Number |
---|---|---|---|
RETINOIDS AND USE THEREOF | 2013 |
|
RU2687285C2 |
IMPROVED METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE TREATMENT OF TELANGIECTASIA | 2011 |
|
RU2535008C2 |
COMPOSITIONS AND METHOD FOR TREATING DISEASED SKIN CONDITIONS | 2011 |
|
RU2578979C2 |
TOPICAL COMPOSITIONS CONTAINING CORTICOSTEROID | 2016 |
|
RU2690659C2 |
TREATMENT OF INFLAMMATORY DAMAGES IN CASE OF ROSAZEA USING IVERMECTIN | 2014 |
|
RU2633481C2 |
OXYMETAZOLINE COMPOSITIONS AND METHODS FOR TREATING OPHTHALMIC DISORDERS | 2020 |
|
RU2820596C2 |
PHARMACEUTICAL COMPOSITION | 1995 |
|
RU2120304C1 |
DERIVATIVES OF SUBSTITUTED UREA, PHARMACEUTICAL COMPOSITION AND DRUG BASED ON THEREOF POSSESSING RETINOID ACTIVITY | 2002 |
|
RU2303027C2 |
ACTIVE DRUG DELIVERY TO DISTANT EYE REGION BY SUBCONJUNCTIVAL OR PERIOCULAR PRODRUG DELIVERY | 2004 |
|
RU2353393C2 |
PHARMACEUTICAL COMPOSITIONS INCLUDING COMBINATION OF CALCITRIOL AND CLOBESATOL PROPIONATE | 2003 |
|
RU2361594C2 |
Authors
Dates
2019-09-03—Published
2016-07-13—Filed