APPLICATION OF Thr-Lys-Pro-Arg-Pro-Gly-Pro PEPTIDE (SELANK) FOR TOXIC HEPATITIS PREVENTION AND TREATMENT Russian patent published in 2017 - IPC A61K38/08 A61P1/16 

Abstract RU 2640133 C1

FIELD: medicine.

SUBSTANCE: application of a peptide of the formula Thr-Lys-Pro-Arg-Pro-Gly-Pro (selank) as a hepatoprotective agent is proposed. The method of the invention comprises administration of a drug based on the heptapeptide of the general formula Thr-Lys-Pro-Arg-Pro-Gly-Pro (selank) by application to the mucosa.

EFFECT: application of the inventions allows to reliably reduce lethality, cytolysis level, metabolic disturbances, increase the activity of the detoxification process, prevent the development of significant changes in liver morphology and cytoarchitectonics.

2 cl, 9 tbl, 2 ex

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RU 2 640 133 C1

Authors

Andreeva Lyudmila Aleksandrovna

Nemerskij Evgenij Alimovich

Petrovskij Aleksej Konstantinovich

Petrovskaya Anastasiya Yurevna

Smirnov Nikolaj Alekseevich

Fedorov Vladimir Nikolaevich

Fedorova Tatyana Borisovna

Dates

2017-12-26Published

2017-08-11Filed