USE OF PEPTIDE Thr-Lys-Pro-Arg-Pro-Gly-Pro (SELANC) HEPATOPROTECTIVE FOR EXPOSURE IN ACUTE IMMOBILISATION STRESS Russian patent published in 2016 - IPC A61K38/08 A61P1/16 

Abstract RU 2582963 C1

FIELD: medicine.

SUBSTANCE: invention relates to use of a peptide having formula Thr-Lys-Pro-Arg-Pro-Gly-Pro (selank) for hepatoprotective effects in acute immobilisation stress.

EFFECT: invention provides a significant increase in hepatic activity of antioxidant enzymes (catalase, SOD), and concentrations of lipid peroxidation products using selank in doses of 100 mcg/kg and 300 mcg/kg.

1 cl, 1 ex, 1 tbl

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RU 2 582 963 C1

Authors

Fomenko Ekaterina Vladimirovna

Krjukov Aleksej Anatolevich

Bobyntsev Igor Ivanovich

Ivanov Aleksandr Viktorovich

Shishov Nikita Mikhajlovich

Dates

2016-04-27Published

2015-04-27Filed