FIELD: nanotechnology.
SUBSTANCE: method for production of Dorogov antiseptic excitor (DAE) nanocapsules fraction 2 in a shell of gellan gum is described. In the method DAE fraction 2 is added to a suspension of gellan gum in ethanol in the presence of 0.01 g of E472c drug as a surfactant at a stirring speed of 1300 rpm. Then hexane is added, the resulting precipitate is filtered and dried at room temperature. The core: shell ratio is 1:1, or 1:3, or 3:1.
EFFECT: simplification and acceleration of the nanocapsules production process and increase in yield by weight.
3 dwg, 4 ex
Authors
Dates
2018-01-09—Published
2016-08-15—Filed