APPLICATION OF CELL LINE OF 369 ADMEL HUMAN SKIN MELANOMA Russian patent published in 2018 - IPC C12N5/00 

Abstract RU 2642265 C1

FIELD: biotechnology.

SUBSTANCE: specialized collection of vertebrata cell cultures of the Russian cell culture collection under the RCCC (P) registration number 727D. The cell line has stable cultural and morphological characteristics, is featured by the expression of differentiation tumor-associated antigens - MelanA, MITF, gp100, S100, tyrosinase, TRP-1; tumor-associated testis-specific antigens - NY-ESO-1 and MAGE, BAGE, GAGE, LAGE families.

EFFECT: invention allows you to test the activity of various pharmaceutical products, create diagnostic sets and test systems to develop new pharmaceuticals and new therapeutic approaches, in particular, allows you to create a model system to determine the optimum doses of photosensitizer for photodynamic therapy, as well as to prepare antitumor vaccine based on activated dendritic cells.

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RU 2 642 265 C1

Authors

Baldueva Irina Aleksandrovna

Danilova Anna Borisovna

Nekhaeva Tatyana Leonidovna

Belyaev Aleksej Mikhajlovich

Dates

2018-01-24Published

2017-06-01Filed