ANTIBODY MOLECULES AGAINST APRIL AND APPLICATIONS THEREOF Russian patent published in 2023 - IPC C07K16/28 A61K39/395 A61P1/00 A61P1/16 A61P13/12 A61P17/00 A61P35/00 A61P29/00 A61P37/06 A61P43/00 A61P9/00 

Abstract RU 2793755 C2

FIELD: biotechnology.

SUBSTANCE: molecule of antibody against a ligand A inducing proliferation (APRIL), method of preparation thereof and also the composition containing the said molecule and the panel. Nucleic acid molecule encoding the variable region of H chain (VH) and the variable region of the L chain of the said antibody molecule and also the containing cell and vector thereof are also disclosed.

EFFECT: treatment of diabetic nephropathy in a subject.

42 cl, 41 dwg, 8 tbl, 13 ex

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RU 2 793 755 C2

Authors

Myette, James, R.

Shriver, Zachary, Holmes

Venkatakrishnan, Karthik

Wollacott, Andrew, M.

Adari-Hall, Hedy

Ramakrishnan, Boopathy

Babcock, Gregory

Dates

2023-04-05Published

2016-11-23Filed