FIELD: pharmacology.
SUBSTANCE: present invention relates to a lyophilized (also known as freeze-dried) drug nanosuspension comprising of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile or its stereoisomeric form or its pharmaceutically acceptable salt and a steric stabiliser, which is a solid at room temperature, and polyvinyl pyrrolidone.
EFFECT: according to the present invention the composition of the lyophilized drug nanosuspension has an acceptable stability of grain-size composition in storage, including long-term storage.
25 cl, 6 dwg, 7 tbl, 2 ex
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