FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine, more specifically to an implanted device comprising a biologically compatible, biologically degradable polymer mixed with TMC278 (rilpivirine) and with one or more release-enhancing agents specified in a group consisting of poloxamers, polysorbates and a combination of dimethylsulphoxide (DMSO) and poly(vinylpyrrolidone) (PVP).
EFFECT: device provides the extended release of the active ingredient for long periods of time.
17 cl, 3 dwg, 5 tbl, 7 ex
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