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2 644 351

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IPC

C07D473/02(2006-01-01)

A61K31/52(2006-01-01)

A61P31/16(2006-01-01)

(21) (22)

Application

2016144712, 2016-11-15

(24)

Start date

2016-11-15

(22)

Actual filing date

2016-11-15

(45)

Published

2018-02-09

(72)

Inventor

Musiyak Vera VasilevnaGalegov Georgij ArtemevichAndronova Valeriya LvovnaKrasnov Viktor PavlovichLevit Galina LvovnaGruzdev Dmitrij AndreevichChulakov Evgenij NikolaevichCharushin Valerij Nikolaevich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Organicheskogo Sinteza Im. I.Ya. Postovskogo Uralskogo Otdeleniya Rossijskoj Akademii Nauk Uro Ran)Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Issledovatelskij Tsentr Epidemiologii I Mikrobiologii Imeni Pochetnogo Akademika N.F. Gamalei" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

-4-[6-(PURINE-6-YLAMINO)HEXANOYL]-3,4-DIHYDRO-3-METHYL-7,8-DIFLUOR-2H-[1,4]BENZOXAZINE AND (3R)-4-[6-(PURINE-6-YLAMINO)HEXANOYL]-3,4-DIHYDRO-3-METHYL-7,8-DIFLUOR-2H-[1,4]BENZOXAZINE WITH ANTIVIRAL ACTIVITY Russian patent published in 2018 - IPC C07D473/02 A61K31/52 A61P31/16

Abstract RU 2644351 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to new purine derivatives of the formulas: .

EFFECT: new derivatives possessing selective antiviral activity against herpes simplex viruses 1 and acting on viral strains with drug resistance to acyclovir and related compounds are obtained.

3 cl, 1 tbl, 3 ex

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RU 2 644 351 C1

Authors

Musiyak Vera Vasilevna

Galegov Georgij Artemevich

Andronova Valeriya Lvovna

Krasnov Viktor Pavlovich

Levit Galina Lvovna

Gruzdev Dmitrij Andreevich

Chulakov Evgenij Nikolaevich

Charushin Valerij Nikolaevich

Dates

2018-02-09—Published

2016-11-15—Filed