FIELD: biotechnology; medicine.
SUBSTANCE: invention relates to biotechnology and medicine, namely to a novel compound used for treating herpetic infection. Compound according to invention is 3-butylthio-1-(beta-D-2-deoxyribofuranosyl)-5-phenyl-(4H)-1,2,4-triazole. Invention also relates to a method of producing a compound according to the invention, comprising cyclisation of benzoylthiosemicarbazide by treatment with a sodium alkali solution, alkylation reaction of obtained 5-phenyl-2,4-dihydro-1,2,4-triazole-3-thione with butyl iodide, enzymatic glycosylation reaction of obtained 3-butylthio-5-phenyl-(4H)-1,2,4-triazole base with 2'-deoxyuridine in K-phosphate buffer solution in the presence of catalytic amounts of uridine phosphorylase (80–200 units) and purine nucleoside phosphorylase (80–200 units).
EFFECT: described is composition 3-butylthio-1-(beta-D-2-deoxyribofuranosyl)-5-phenyl-(4H)-1,2,4-triazole for treating herpetic infection.
3 cl, 2 dwg, 4 tbl, 6 ex
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