MODIFIED CELLS WITH CHIMERIC ANTIGEN RECEPTOR FOR TREATING CANCER EXPRESSING CLDN6 Russian patent published in 2024 - IPC C07K16/28 C07K14/705 C12N5/783 A61K35/17 A61P35/00 

Abstract RU 2826058 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to a chimeric antigen receptor (CAR) molecule which recognizes CLDN6, a kit containing it, as well as a nucleic acid which codes it. Also disclosed is a vector, a cell and a population of cells containing said nucleic acid.

EFFECT: invention is effective for treating a disease associated with expression of CLDN6, as well as for stimulating a cell-mediated immune response to a CLDN6 expressing target cell population or tissue in a subject.

51 cl, 10 dwg, 11 ex

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RU 2 826 058 C2

Authors

Sahin, Ugur

Oehm, Petra

Rengstl, Benjamin

Reinhard, Katharina

Michel, Kristina

Dates

2024-09-03Published

2020-02-05Filed