FIELD: biotechnology.
SUBSTANCE: invention relates to a chimeric antigen receptor (CAR) molecule which recognizes CLDN6, a kit containing it, as well as a nucleic acid which codes it. Also disclosed is a vector, a cell and a population of cells containing said nucleic acid.
EFFECT: invention is effective for treating a disease associated with expression of CLDN6, as well as for stimulating a cell-mediated immune response to a CLDN6 expressing target cell population or tissue in a subject.
51 cl, 10 dwg, 11 ex
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Authors
Dates
2024-09-03—Published
2020-02-05—Filed