HIGH-STABLE T-CELL RECEPTOR AND METHOD FOR ITS OBTAINING AND APPLICATION Russian patent published in 2018 - IPC C07K14/725 C12N15/12 C12N15/70 C12N5/10 A61K35/12 A61K38/17

Abstract RU 2645256 C2

FIELD: biotechnology.

SUBSTANCE: highly stable T-cell receptor is proposed that can be used in medicine. The resulting T-cell receptor having mutations in its hydrophobic core domain is used in a pharmaceutical composition for tumour treatment.

EFFECT: invention allows effective therapy of diseases associated with formation of tumours.

25 cl, 49 dwg, 13 tbl, 16 ex

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RU 2 645 256 C2

Authors

Li I

Dates

2018-02-19—Published

2014-06-25—Filed