PHARMACEUTICAL COMPOSITIONS AS RECTAL SUPPOSITORIES CONTAINING NEFOPAM HYDROCHLORIDE (VERSIONS), THEIR APPLICATION FOR TREATMENT OF ACUTE AND CHRONIC PAIN SYNDROME AND METHODS FOR PRODUCTION Russian patent published in 2018 - IPC A61K9/02 A61K31/395 A61P25/04 

Abstract RU 2646495 C2

FIELD: pharmacology.

SUBSTANCE: invention refers to the application of nefopam hydrochloride in the form of rectal suppositories on hydrophilic emulsion basis, including polyethylene oxide 400 solvent, for treatment of acute and chronic pain syndrome.

EFFECT: invention provides efficient analgesic effect of rectal suppositories containing nefopam hydrochloride, comparable in effectiveness and duration with analgesic action of nefopam hydrochloride at intramuscular administration.

7 cl, 7 tbl, 5 ex

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RU 2 646 495 C2

Authors

Abuzarova Guzal Rafailovna

Alekseeva Galina Sergeevna

Bezuglaya Elena Petrovna

Libina Viktoriya Vitalevna

Lyapunov Aleksej Nikolaevich

Lyapunov Nikolaj Aleksandrovich

Nespovityj Gennadij Vladimirovich

Dates

2018-03-05Published

2015-12-28Filed