FIELD: pharmaceuticals.
SUBSTANCE: group of inventions relates to pharmaceutical industry, namely to a pharmaceutical composition for the treatment of acute and chronic pain syndrome in the form of rectal suppositories, containing in 100 g of the composition 0.40–8.00 g of nefopam hydrochloride in micronized form and a lipophilic base (up to 100 g); as well as to a process for preparing said composition, according to which the micronized non-ophamate hydrochloride substance is suspended in a molten lipophilic base.
EFFECT: group of inventions ensures provision of storage-stable suppositories of analgesic action comparable in effectiveness and duration with such an effect when administered intramuscularly.
4 cl, 1 ex, 5 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| PHARMACEUTICAL COMPOSITIONS AS RECTAL SUPPOSITORIES CONTAINING NEFOPAM HYDROCHLORIDE (VERSIONS), THEIR APPLICATION FOR TREATMENT OF ACUTE AND CHRONIC PAIN SYNDROME AND METHODS FOR PRODUCTION | 2015 |
|
RU2646495C2 |
| NEPHOPAM SUPPOSITORIES FOR THE TREATMENT OF ACUTE AND CHRONIC PAIN SYNDROME ON A HYDROPHILIC EMULSION BASED AND METHOD FOR THEIR PREPARATION | 2017 |
|
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| SUPPOSITORIES FOR TREATMENT OF MODERATE AND HIGH-INTENSITY PAIN SYNDROME | 2019 |
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| SUPPOSITORIES FOR TREATMENT OF MODERATE AND HIGH-INTENSITY PAIN SYNDROME | 2019 |
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| SUPPOSITORIES FOR TREATMENT OF MODERATE AND HIGH-INTENSITY PAIN SYNDROME | 2019 |
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| SUPPOSITORIES FOR TREATMENT OF MODERATE AND HIGH-INTENSITY PAIN SYNDROME | 2019 |
|
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| PHARMACEUTICAL COMPOSITION CONTAINING NALBUPHINE HYDROCHLORIDE, USING IT FOR TREATING MODERATE TO SEVERE PAIN SYNDROME | 2012 |
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| METHOD OF TREATING CHRONIC PAIN SYNDROME | 2014 |
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| MEDICAL FORM FOR TRANS-MUCOUSAL PERORAL INTRODUCTION OF ANALGESIC AND/OR ANTISPASMODIC MOLECULES | 2010 |
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| METHOD FOR PREANAESTHETIC MEDICATION PRECEDING GYNAECOLOGICAL SURGERIES UNDER GENERAL ANAESTHESIA | 2014 |
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