FIELD: biotechnology.
SUBSTANCE: present invention refers to new immunogens based on overlapping peptides (OLP), and can be used in medicine for preventing or treating HIV infection. Immunogenic fused protein consisting of polypeptide segments connected by amino acid linkers is obtained. Present invention also relates to isolated nucleic acids, vectors and host cells expressing these immunogens, as well as vaccines containing said immunogens.
EFFECT: invention provides induction of HIV-specific T-cell immune responses in a host.
36 cl, 8 dwg, 5 tbl, 4 ex
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