FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, specifically to a new HIV immunogens, and can be used in medicine for treating or preventing a disease caused by HIV infection. Polypeptide - version gp120 HIV-1 with SEQ ID NO: 4 is taken by method of fast extraction immunogens (RIS) based on the binding a library of recombinant viruses, containing randomized HIV gp120 variants of a surface polypeptide located on the antibodies with neutralizing activity.
EFFECT: invention enables effectively induce antibodies with neutralizing activity against HIV-1.
7 cl, 5 dwg, 1 tbl
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Authors
Dates
2016-11-27—Published
2012-02-24—Filed