RAPID SELECTION METHOD FOR HIV GP-120 VARIANTS Russian patent published in 2016 - IPC C07K14/16 A61K39/21 C12N15/10 

Abstract RU 2603732 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, specifically to a new HIV immunogens, and can be used in medicine for treating or preventing a disease caused by HIV infection. Polypeptide - version gp120 HIV-1 with SEQ ID NO: 4 is taken by method of fast extraction immunogens (RIS) based on the binding a library of recombinant viruses, containing randomized HIV gp120 variants of a surface polypeptide located on the antibodies with neutralizing activity.

EFFECT: invention enables effectively induce antibodies with neutralizing activity against HIV-1.

7 cl, 5 dwg, 1 tbl

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RU 2 603 732 C2

Authors

Juste Errans Marija Eloiza

Sanches Merino Viktor

Ferrejra Karolina

Dates

2016-11-27Published

2012-02-24Filed