COMPOSITION FOR PREVENTING OR TREATING RENAL DISEASES, CONTAINING DPP-IV INHIBITOR Russian patent published in 2018 - IPC A61K31/4965 A61K31/495 A61P13/12 

Abstract RU 2652343 C2

FIELD: pharmaceuticals.

SUBSTANCE: present invention relates to the field of pharmaceutics and discloses a composition for the prevention or treatment of renal diseases. Composition of the present invention contains the compound (R)-4-{(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl}-3-(tert-butoxymethyl)piperazin-2-one, or pharmaceutically acceptable salts; or hydrate or solvate thereof.

EFFECT: claimed composition improves lipid metabolism, prevents histological damage, including renal fibrosis, facilitates microalbuminuria and supports nephrons of renal glomeruli and can be used to treat renal diseases.

7 cl, 18 dwg, 2 tbl, 10 ex

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RU 2 652 343 C2

Authors

Cha Dae Riong

Kang Joung Sun

Cha Dzin Dzoo

Li Dzi Eun

Kim Khiun Vook

Li Mi Khva

Kim Dzung Eun

Kim Mi-Kiung

Son Moon-Kho

Kim Soon Khoe

Dates

2018-04-25Published

2014-06-17Filed