FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention relates to the pharmaceutical industry, and in particular to a composition for preventing or treating aortic valve calcification. Use of a pharmaceutical composition containing a dipeptidyl peptidase-4 (DPP-4) inhibitor for preventing or treating aortic valve calcification, where the inhibitor is at least one selected from the group consisting of sitagliptin, alogliptin, evogliptin, linagliptin, saxagliptin and vildagliptin. Use of a dipeptidyl peptidase-4 (DPP-4) inhibitor to obtain a medicament for the prevention or treatment of aortic valve calcification, where the inhibitor is at least one selected from the group consisting of sitagliptin, alogliptin, evogliptin, linagliptin, saxagliptin and vildagliptin. Use of a composition containing a dipeptidyl peptidase-4 (DPP-4) inhibitor for preventing or treating aortic valve calcification, where the inhibitor is at least one selected from the group consisting of sitagliptin, alogliptin, evogliptin, linagliptin, saxagliptin and vildagliptin.
EFFECT: above composition is effective in preventing or treating aortic valve calcification.
5 cl, 11 dwg, 2 tbl, 7 ex
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