METHOD FOR CLEARING DISULFO DERIVATIVE DIAMINO TRIPHENYLMETHANE DYE Russian patent published in 2018 - IPC C09B67/54 B01J20/26 A61K49/04 

Abstract RU 2654862 C1

FIELD: technological processes.

SUBSTANCE: invention relates to a method for purifying impurity derivatives of a diaminotriphenylmethane dye from a disulfo derivative for subsequent use as a contrast agent in the detection of regional lymphogenous metastasis of malignant tumors in tumors of different localization, as well as in food, drugs, cosmetics, etc. Method for purifying a disulfo derivative of a diaminotriphenylmethane dye is proposed, which consists in adsorption of a disulfo derivative of a diaminotriphenylmethane dye on a sorbent element in the form of a plate of polydimethylsiloxane. Result is a disulfo derivative of diaminotriphenylmethane dye with a purity of at least 99.8 % with simplification of the purification technology.

EFFECT: proposed method is simple in execution, easily scalable and characterized by a low cost price.

8 cl, 3 dwg, 2 ex

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RU 2 654 862 C1

Authors

Tonevitskij Aleksandr Grigorevich

Gazizov Ildar Nafisovich

Poloznikov Andrej Aleksandrovich

Dates

2018-05-23Published

2017-10-24Filed