DEVICE FOR USE IN DETECTION OF BINDING AFFINITIES Russian patent published in 2018 - IPC G01N21/77 

FIELD: instrument making.

SUBSTANCE: present invention relates to device, used for detection of binding affinities, as well as a method for detecting binding affinities according to a corresponding independent item. Device (1) for use in the detection of binding affinities comprises planar waveguide (2) arranged on substrate (22). Waveguide (2) has outer surface (21) and a plurality of incoupling lines (31) for coupling a beam of coherent light into waveguide (2) such that a parallel beam of coherent light (62) propagates along waveguide (2). Incoupling lines (31) are curved and have an increasing distance between adjacent incoupling lines (31). Divergent beam of coherent light (61) of a predetermined wavelength is coupled into waveguide (2) such that it propagates along waveguide (2). Plurality of binding sites (51) is attached to outer surface (21) along at least one further plurality of diffraction lines arranged in an outcoupling section of waveguide (2). These diffraction lines comprise a plurality of curved outcoupling lines (41) having a decreasing distance between adjacent outcoupling lines. They decouple a diffracted portion of coherent light from planar waveguide (2), and the decoupled portion of coherent light (63) converges into predetermined second focal location (631).

EFFECT: technical result is reduced distortion of results.

15 cl, 9 dwg