METHOD FOR PREPARING OUTER SURFACE OF PLANAR WAVEGUIDE TO BE CAPABLE OF BINDING TARGET SAMPLES ALONG PLURALITY OF PREDETERMINED LINES AND PLANAR WAVEGUIDE Russian patent published in 2018 - IPC G01N33/543 

FIELD: optics.

SUBSTANCE: group of inventions relates to the field of surface preparation of a planar waveguide, which is able to bind target samples. This method for preparing the outer surface of the planar waveguide, which is able to bind target samples along a plurality of predetermined lines, contains the following steps: providing a planar waveguide having an outer surface adapted to attach linker molecules to the outer surface; sequential application of at least one plurality of linker molecules on the outer surface, wherein each plurality of at least one plurality of linker molecules is assembled to form an individual layer of linker molecules, with the individual layers being formed one above the other, starting from the outer surface of the planar waveguide, each linker molecule contains a functional group and a head group, and the head group is able to attach to the outer surface of the planar waveguide or the functional groups of the preceding layer of linker molecules, in which the functional groups of the linker molecules from the uppermost layer are abound with photo-labile protecting groups, so that each functional group of the uppermost layer bound to the photolabile protective group is not able to attach a complementary functional group of the additional molecule; and exposing these photolabile protective groups of the uppermost layer, arranged along a plurality of predetermined lines to light of a predetermined wavelength to remove the exposed photolabile protective groups from the functional groups to give these functional groups the ability to attach a complementary functional group of an additional molecule, with the additional molecule being a capture molecule, a modified capture molecule or a linker molecule. Also a planar waveguide is disclosed, having an outer surface prepared for bonding with the target samples along a plurality of predetermined lines.

EFFECT: group of inventions provides constructive interference of coherent light by scattering coherent light introduced and propagating through a planar waveguide with a field of damped oscillations of coherent light on target samples located along a plurality of predetermined lines.

24 cl, 24 dwg