DEVICE USED FOR DETECTING OF BINDING AFFINITY Russian patent published in 2017 - IPC G01N21/55 G01N21/77 G01N33/543 

FIELD: biotechnology.

SUBSTANCE: invention relates to devices used for detecting binding affinity and can be used in biosensors. Device contains planar waveguide (2), arranged on substrate (3), and optical isolation (4) for output of coherent light (1) of preset wave length into planar waveguide. Coherent light passes through planar waveguide (2), and evanescent field (6) spreads along outer surface (5) of planar waveguide. Outer surface (5) of planar waveguide contains binding sites (7), able to bind target samples (8) on it with binding sites (7) so, that light of evanescent field (6) is scattered by target samples (8), associated with binding sites (7). Binding sites (7) are arranged along multiple specified lines (9), arranged so, that scattered light structurally interferes in specified detection position with difference of optical path length, being whole multiple of given wavelength.

EFFECT: technical result is high efficiency of detecting, universality of design.

24 cl, 21 dwg