SULPHATE SALTS OF N-(3-(4-(3-(DIISOBUTYLAMINO)PROPYL)PIPERAZIN-1-YL)PROPYL)-1H-BENZO[D]IMIDAZOLE-2-AMINE, PREPARATION THEREOF AND USE OF SAME Russian patent published in 2018 - IPC C07D235/30 A61K31/4184 A61P25/28 

Abstract RU 2655454 C2

FIELD: organic chemistry.

SUBSTANCE: invention relates to organic chemistry, particularly sulphate of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazole-2-amine of formula II and its pharmaceutically acceptable hydrate. Invention also relates to a pharmaceutical composition based on said sulphate.

.

EFFECT: technical result: a novel salt of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazole-2-amine, characterised by improved physical characteristics, such as increased stability and low hygroscopicity.

11 cl, 30 dwg, 7 ex, 4 tbl

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RU 2 655 454 C2

Authors

Byurle Stefan

Estrella Sesiliya

Bare Mate

Melnik Patrisiya

Serzhan Nikola

Byue Lyuk

Vervard Filipp

Dates

2018-05-29Published

2013-12-27Filed