FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, specifically to the production of antibodies against interleukin-6, and can be used in medicine. Resulting antibody or antigen-binding fragment thereof is used in a pharmaceutical composition, as well as for the preparation of medicaments for the treatment or diagnosis of diseases or for the relief of symptoms, which are mediated by interleukin-6. Nucleic acid molecule, the expression vector and the cell line are also studied. In addition, the method for producing the antibody and its antigen-binding fragment is described.
EFFECT: invention provides for the obtainment of the anti-IL6 antibody, which is capable of specifically binding to the human interleukin-6 receptor and has a significant inhibitory effect on the function of interleukin-6.
19 cl, 18 dwg, 21 ex, 8 tbl
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