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2 433 138

(13)

(51)

IPC

C07K16/28(2006-01-01)

C12N15/13(2006-01-01)

C12N15/63(2006-01-01)

A61K39/395(2006-01-01)

A61P29/00(2006-01-01)

A61P19/02(2006-01-01)

(21) (22)

Application

2008152443/10, 2007-06-01

(24)

Start date

2007-06-01

(22)

Actual filing date

2007-06-01

(45)

Published

2011-11-10

(72)

Inventor

Stivens ShonKhuan Tammi T.Martin Dzhoehl Kh.Fehrkherst Zhanetta L.Rafik AshikSmit EhrikPoburski Kevin Dzh.Papadopulos Nikolas Dzh.Fehnld Dzhejms P.Chehn' GanKarou Margaret

(73)

Holder

Ridzheneron Farmas'Jutikalz, Ink.

ANTIBODIES OF HIGH AFFINITY TO IL-6-RECEPTOR OF HUMANS Russian patent published in 2011 - IPC C07K16/28 C12N15/13 C12N15/63 A61K39/395 A61P29/00 A61P19/02

Abstract RU 2433138 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed invention relates to field of immunology and biotechnology. Claimed are: versions of antibody and antigen-binding fragments of antibody to receptor Il-6 of humans. Considered are: isolated molecule of nucleic acid and vector which contains it. Described are: system "host-vector" and method of obtaining antibody or its antigen-binding fragment, as well as application of antibody or its antigen-binding fragment for obtaining medication.

EFFECT: invention application provides novel antibodies to receptor IL-6 of humans, which can be applied in therapy of IL-6- mediated diseases.

11 cl, 5 tbl, 7 ex

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RU 2 433 138 C2

Authors

Stivens Shon

Khuan Tammi T.

Martin Dzhoehl Kh.

Fehrkherst Zhanetta L.

Rafik Ashik

Smit Ehrik

Poburski Kevin Dzh.

Papadopulos Nikolas Dzh.

Fehnld Dzhejms P.

Chehn' Gan

Karou Margaret

Dates

2011-11-10—Published

2007-06-01—Filed