METHOD OF INCREASING OSMOTIC RESISTANCE OF ERYTHROCYTE MEMBRANES Russian patent published in 2018 - IPC A61K31/715 A61K36/882 A61K125/00 A61P35/00 

Abstract RU 2659127 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely, to experimental oncology, and can be used to increase the osmotic resistance of erythrocyte membranes under conditions of experimental carcinogenesis of liver and oesophagus induced by N-nitrosodiethylamine. To create model of intoxication to animals together with drinking water for 4 months N-nitrosodiethylamine amine is introduced in dose of 100 mg/l, and as a means of increasing the osmotic resistance of erythrocyte membranes, polysaccharides of sweet flag are introduced with food in dose of 75 mg/kg of body weight for 6 months.

EFFECT: invention provides higher resistance of membranes, thus promoting reduction percentage of laked blood cells and increases their viability under conditions of experimental carcinogenesis.

1 cl, 1 dwg, 1 ex

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RU 2 659 127 C1

Authors

Kokoev Leonid Aleksandrovich

Bolieva Laura Zelimkhanovna

Kaboeva Bella Nikolaevna

Belousov Mikhail Valerevich

Gurev Artem Mikhajlovich

Yusubov Mekhman Sulejmanovich

Dates

2018-06-28Published

2017-04-27Filed