FIELD: pharmaceutics.
SUBSTANCE: invention relates to pharmaceutical industry. Use of a composition of alkyl-glycerol esters derived from marine organisms containing 94 % chemical alcohol is proposed as a means of reducing neuropathic pain. Invention can be used to reduce the pain sensitivity of the organism both with the use of an individual composition of alkyl-glycerol esters and in combination with other substances having a biological effect.
EFFECT: property of alkyl-glycerol esters derived from sea lipids was found to reduce neuropathic pain and its cognitive effects by preventing activation of M1 microglia and normalization of neurogenesis in the hippocampus.
1 cl, 5 dwg, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR TREATMENT OF NEUROPATHIC PAIN | 2021 |
|
RU2780139C1 |
| AGENT STIMULATING NEUROGENESIS IN ISCHEMIC CEREBRAL INJURIES | 2015 |
|
RU2585094C1 |
| ACTIVE DRUG INGREDIENT, DRUG, PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATMENT OF DEMYELINATING DISEASES OF LIVING ORGANISM, INCLUDING DISEASE PREVENTION | 2015 |
|
RU2631887C2 |
| AGENT FOR STIMULATING BODY ADAPTATION TO EXTREMAL AND STRESS FACTORS AND METHOD OF STIMULATING BODY ADAPTATION TO EXTREMAL AND STRESS FACTORS | 2018 |
|
RU2683311C1 |
| NEW TREATMENT OF MULTIPLE SCLEROSIS (MS) | 2011 |
|
RU2595861C2 |
| METHOD FOR STIMULATING NEUROGENESIS IN THE HIPPOCAMPUS | 2017 |
|
RU2675111C2 |
| INTERLEUKIN-10, USING IT AND BASED COMPOSITION FOR TREATING BRAIN NEURODEGENERATIVE PROCESSES | 2012 |
|
RU2538613C2 |
| BIOTHERAPY METHOD OF LABORATORY RATS WITH GRAFTED GLIOBLASTOMA | 2019 |
|
RU2722268C1 |
| NGF AND TrkA RECEPTOR BINDING INHIBITING MOLECULES AS PROLONGED ANALGESICS | 2006 |
|
RU2427387C2 |
| USE OF BENZOATE FOR TREATMENT OF DISORDERS OF CENTRAL NERVOUS SYSTEM | 2017 |
|
RU2780450C2 |
