FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine, and concerns NGF and TrkA receptor binding inhibiting molecules as prolonged analgesics. Substance of the invention involves application of anti-NgF antibodie, isotype IgG4 inhibiting NGF and TrkA binding and blocking biological TrkA activity for preparing a drug for treatment and/or prevention of chronic pain. A method of treatment of chronic pain is declared also.
EFFECT: analgesic effect prolongation.
41 cl, 1 tbl, 6 dwg
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