FIELD: biochemistry.
SUBSTANCE: invention relates to biochemistry, in particular to a single-stranded oligonucleotide, where all nucleosides of the oligonucleotide are 2'-O-alkyl-ribonucleosides, as well as the use of said oligonucleotide in the treatment of cystic fibrosis of the human body or animal body. Also disclosed is a complex for the treatment of cystic fibrosis of the human body or animal body, comprising said oligonucleotide. Invention also relates to a pharmaceutical composition for the treatment of cystic fibrosis comprising said oligonucleotide.
EFFECT: invention enables to effectively treat cystic fibrosis.
19 cl, 9 dwg, 2 ex
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