FIELD: biotechnology.
SUBSTANCE: present invention relates to biotechnology. According to this invention, a nucleotide sequence, in which base constituent elements thereof are modified, and a specific combination of such sequences are useful in compositions for effectively treating diseases associated with human papillomavirus (HPV) infection by strongly inhibiting the expression of E6/E7 HPV type 18 gene.
EFFECT: compositions for preventing or treating diseases associated with HPV are proposed.
6 cl, 8 dwg, 4 tbl, 1 ex
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