METHODS OF DIAGNOSIS AND COMPOSITION FOR CANCER TREATMENT Russian patent published in 2018 - IPC G01N33/50 C12Q1/68 

FIELD: medicine.

SUBSTANCE: proposed group of inventions relates to medicine. Methods for determining and selecting therapy for a patient and a kit for determining whether a patient can benefit from treatment with a VEGF antagonist are provided. Detection of Cox2 expression in a patient's biological sample is carried out before the introduction of the VEGF antagonist, the level of Cox2 expression is compared with the reference level, where to increase the expression of Cox2 in a patient sample relative to the reference expression level, a patient is identified that is likely to respond to treatment with a VEGF antagonist.

EFFECT: proposed group of inventions provides effective means and methods for determining whether a patient can benefit from treatment with the help of a VEGF antagonist by detecting the expression of Cox2 in a biological sample of the patient.

51 cl, 8 dwg, 4 tbl, 4 ex